Academic Year/course:
2017/18
452 - Degree in Chemistry
27220 - Laboratory Methods and Quality Control
Syllabus Information
Academic Year:
2017/18
Subject:
27220 - Laboratory Methods and Quality Control
Faculty / School:
100 - Facultad de Ciencias
Degree:
452 - Degree in Chemistry
ECTS:
6.0
Year:
4
Semester:
First semester
Subject Type:
Compulsory
Module:
---
5.1. Methodological overview
The methodology followed in this course is oriented towards achievement of the learning objectives. It favors the understanding of the different chemical processes that occur in the environment. A wide range of teaching and learning tasks are implemented, such as theory sessions, laboratory sessions, assignments, and tutorials.
Students are expected to participate actively in the class throughout the semester.
Classroom materials will be available via Moodle. These include a repository of the lecture notes used in class, the course syllabus, as well as other course-specific learning materials.
Further information regarding the course will be provided on the first day of class.
5.2. Learning tasks
Activity 1: Quality Control and validatition of analytical methods (2 ECTS)
- Participatory lectures: 20 h
- Self-assessment work: 25h
- Examination: 3h
Activity 2: Learn the use of the addequate software and spreadsheets for quality control and validation of analytical methods (1 ECTS).
- Documentation and problem solving in computer lab sessions: 10h.
- Self-assessment work: 15h
- Examination: 2h
Activity 3: Implementation and validation of analytical methods in the laboratory (3.0 ECTS).
- Laboratory work: 30h
- Data treatment and repport of the results : 40h of self-assessment work.
- Presententation and defense of the results: 5h
5.3. Syllabus
Chapter 1: Introduction to the Quality.
i-Quality and Quality Management Systems. Ii- Q Components. Iii- Historical stages in Quality. Iv- Implementation and support of a Q Management System.
Chapter 2: Quality in Chemical laboratories.
i- Quality and labs types.Ii- Q and analytical properties.
Iii-Activities in the Analytical laboratory.iv- Examples of Q and not Q.v- Principal elements in Q. vi- Keystones: Q assurance and Q control. Vii-Metrology: primary standard and certified reference materials. Viii- Traceability ix- Documentation.
Chapter 3- Quality Standards
i-Q structure. Ii- Q Management system in the labs: standardization-accreditation-certification. Iii- Accreditation: iso 17025: overview. Iv- Good laboratory practices-:GLP model. V- QA unity in GLP. Vi- Scope in QA programs in GLP.
Chapter 4. Statistic tools for Q.
i-Analytical data and results. Ii- Analysis of Variance. Iii- Uncertainty iv-Control Charts.
Chapter 5- Selection and design of the analytical method.
i-Analytical information: data bases. ii-Analytical method selection. Iii- Parameters of the analytical methods. Iv- Optimization and experimental designs.
Chapter 6- Analytical method validation.
i-Q assessment in the analytical lab.ii- Analytical method validation iii- Robustness iv- QC and QA. Iv- Internal and external assessments. V- Interlaboratory tests.
5.4. Course planning and calendar
Lectures: 2h por week during the first semester to complete the total 20h.
Problems: 5 computer lab sessions of 2h during the first semester.
Practical sessions: the schedule and the work group will be available for students at the beginning of the course in the Moodle platform.
5.5. Bibliography and recommended resources
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BB
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Compañó Beltrán, Ramon. Garantía de la calidad en los laboratorios analíticos / Ramón Compañó Beltrán, Ángel Ríos Castro Madrid : Síntesis, 2002
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BC
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Funk, W.; Dammann, V.; Donnevert, G.. Quality Assurance in Analytical Chemistry. Wiley-Blackwell. 2006
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BC
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Miller, James N.. Estadística y Quimiometría para química analítica / James N. Miller, Jane C. Miller ; traducción, Carlos Maté Jiménez, Roberto Izquierdo Hornillos . - 1ª ed. en español Madrid : Prentice Hall, 2002
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Online resources:
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AENOR - [http://www.aenor.es]
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ENAC- [http://www.enac.es]
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ISO - [http://www.iso.org]
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